SOX-11 Antibody (DA135)
SOX-11 Antibody (DA135)
Recombinant monoclonal rabbit antibody
Description
SOX-11 which is a member of the SOX (SRY-related HMG-box) family is a transcription factor normally expressed in the developing human central nervous system and plays a role in embryonic cell determination.1,3 Studies show that SOX-11 can be used as a marker for mantle cell lymphoma (MCL).2,3
References
1. Hargrave, M et al. Expression of the SOX-11 gene in mouse embryos suggests roles in neuronal maturation and epithelio-mesenchymal induction. Dev Dyn 1997; 210:79-86.
2. Zeng W, et al. Cyclin D1-negative blastoid mantle cell lymphoma identified by SOX-11 expression. Am J Surg Pathol 2012; 36:214-9.
3. Narurkar R, et al. SOX11 is a biomarker for cyclin D1-negative mantle cell lymphoma. Biomark Res. 2016; 4:6.
2. Zeng W, et al. Cyclin D1-negative blastoid mantle cell lymphoma identified by SOX-11 expression. Am J Surg Pathol 2012; 36:214-9.
3. Narurkar R, et al. SOX11 is a biomarker for cyclin D1-negative mantle cell lymphoma. Biomark Res. 2016; 4:6.
Specifications
Application:
IHC (FFPE)
Host:
Rabbit
Subclass:
IgG
Immunogen:
Synthetic peptide of human SOX-11
Cellular location:
Nucleus
Control:
Colon Carcinoma
Order information
| DMRD0165 | Concentrate | IVD(R) |
| DMRD0165 | 10 ml Ready to use | IVD(R) |
| DMRD0165 | 6 ml Ready to use | IVD(R) |
| DMRD0165 | 3 ml Ready to use | IVD(R) |
