Carbonic Anhydrase IX Antibody (DA141)
Carbonic Anhydrase IX Antibody (DA141)
Recombinant monoclonal mouse antibody
Description
Carbonic Anhydrase (CA IX) is part of a family of zinc containing metalloproteins that catalyze the reversible hydration of CO2.1 Among these, CA IX is anchored to the cell membrane and is expressed in the human gastrointestinal tract, chiefly in the stomach.1 Data suggest consistent immunoreactivity for anti-CA IX in clear cell renal cell carcinoma (RCC) making it a useful marker for this type of tumor.2
References
1. Leppilampi, M et al. Carbonic anhydrase isozymes IX and XII in gastric tumors. World J Gastroenterol. 2003; 9:1398-1403.
2. Gupta, R et al. Diagnostic implications of transcription factor Pax 2 protein and transmembrane enzyme complex carbonic anhydrase IX immunoreactivity in adult renal epithelial neoplasms. Am J Surg Pathol. 2009; 33:241-7.
2. Gupta, R et al. Diagnostic implications of transcription factor Pax 2 protein and transmembrane enzyme complex carbonic anhydrase IX immunoreactivity in adult renal epithelial neoplasms. Am J Surg Pathol. 2009; 33:241-7.
Specifications
Application:
IHC (FFPE)
Host:
Mouse
Subclass:
IgG2a/κ
Immunogen:
Synthetic peptide of human Carbonic Anhydrase IX
Cellular location:
Cell membrane
Control:
Clear Cell Renal Cell Carcinoma
Order information
| DMRD0176 | Concentrate | IVD(R) |
| DMRD0176 | 10 ml Ready to use | IVD(R) |
| DMRD0176 | 6 ml Ready to use | IVD(R) |
| DMRD0176 | 3 ml Ready to use | IVD(R) |
