CD61 Antibody (DA149)
CD61 Antibody (DA149)
Recombinant monoclonal rabbit antibody
Description
CD61 also known as integrin beta chain beta 3 (ITGB3) is an integrin cell-surface protein associated with cellular adhesion and cell-surface mediated signaling. Immunohistochemical staining for CD61 can be useful in evaluating normal and abnormal megakaryocytes, which can aide in the identification of some hematopoietic malignancies. Anti-CD61 reactivity is also seen in platelets, osteoclasts and macrophages.1-4
References
1. Thiele J, et al. An immunomorphometric study on megakaryocyte precursor cells in bone marrow tissue from patients with chronic myeloid leukemia (CML). Eur J Haematol. 1990; 44:63-70.
2. Thiele J, et al. Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies. Anal Quant Histol. 1990; 12:285-9.
3. Fox SB, et al. Megakaryocytes in myelodysplasia: an immunohistochemical study on bone marrow trephines. Histopathology. 1990; 17:69-74.
4. Thiele J, et al. Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies. Anal Quant Histol. 1990; 12:285-9.
2. Thiele J, et al. Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies. Anal Quant Histol. 1990; 12:285-9.
3. Fox SB, et al. Megakaryocytes in myelodysplasia: an immunohistochemical study on bone marrow trephines. Histopathology. 1990; 17:69-74.
4. Thiele J, et al. Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies. Anal Quant Histol. 1990; 12:285-9.
Specifications
Application:
IHC (FFPE)
Host:
Rabbit
Subclass:
IgG
Immunogen:
Synthetic peptide of human CD61
Cellular location:
Cytoplasm/Cell membrane
Control:
Bone Marrow
Order information
| DMRD0185 | Concentrate | IVD(R) |
| DMRD0185 | 10 ml Ready to use | IVD(R) |
| DMRD0185 | 6 ml Ready to use | IVD(R) |
| DMRD0185 | 3 ml Ready to use | IVD(R) |
